Effect of Vitamins A, C, and E Supplementation in the Treatment of Metabolic Syndrome in Albino Rats

Table 4

Effect of supplementation on antioxidant enzymes and nitric oxide.

Group	Catalase	GPx	SOD	Nitric oxide
	(nmol/min/mL)	(nmol/min/mL)	(U/mL)	(𝜇M)
I	26.27 ± 4.47	95.76 ± 9.75	5.21 ± 1.46	28.14 ± 3.85
II	14.52 ± 3.16^c	28.01 ± 7.26^c	2.86 ± 0.62^c	17.70 ± 3.07^c
III	23.76 ± 5.84^a	73.34 ± 11.62^a,d	5.49 ± 1.06^a	28.59 ± 4.86^a
IV	21.48 ± 3.70	61.88 ± 10.44^a,c	4.93 ± 0.83^b	29.33 ± 4.30^a
V	24.65 ± 3.19^a	78.19 ± 10.40^a	6.38 ± 0.58^a	26.96 ± 4.87^a
VI	22.16 ± 4.14^b	72.58 ± 12.86^a,c	6.01 ± 1.28^a	22.81 ± 3.51

GPx: glutathione peroxidase, SOD: superoxide dismutase, I: normotensive control, II: hypertensive control, III: group treated with vit C, IV: group treated with vit A, V: group treated with vit E, and VI: group treated with all the vitamins. Values are expressed as mean ± SD; 𝑛=5. ^aP < 0.01 when compared with group II, ^bP < 0.05 when compared with group II, ^cP < 0.01 when compared with group I, and ^dP < 0.05 when compared with group I by Dunnette’s multiple comparison test.