Research Article

Overexpression of PGC-1α Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells

Figure 7

Effects of PGC-1α overexpression on mRNA expression of fiber-type marker genes MHCI and MHCIIa. mRNA was isolated from cultured myotubes infected with either empty control vector or PGC-1α, eight days after the onset of differentiation. Gene expression was assessed by RT-PCR, and values are presented as means ± SEM of 3 experiments, each representing one donor, with 3 replicates each, normalized to the levels of housekeeping gene 36B4. *Significantly different from cells infected with empty control vector at .
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