Research Article

Effects of Spirulina on Cyclophosphamide-Induced Ovarian Toxicity in Rats: Biochemical and Histomorphometric Evaluation of the Ovary

Table 1

Biochemical analysis of the ovarian CAT, SOD activities, and MDA levels.

CAT (U/gr)SOD (U/gr)MDA (nmol/gr)

C (#6)155.35 ± 25.02137.88 ± 21.331.39 ± 1.02
CP (#6)128.74 ± 11.48b 87.86 ± 15.21a3.10 ± 0.86a
Sp+Cyc (#6)146.04 ± 22.07b117.45 ± 24.79b1.90 ± 0.72b

CAT: catalase, SOD: superoxide dismutase, MDA: malonedialdehyde, C: control group, CP: cyclophosphamide group, Sp+Cyc: Spirulina+cyclophosphamide group. Values are expressed as mean ± SEM. aStatistically significant difference between the groups C and CP for SOD activity and MDA level ( ). bNo statistically significant difference between the groups C and CP for CAT activity and between the groups C and Sp+Cyc for CAT, SOD activities, and MDA levels ( ).