Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine

Table 5

Values of SPA, TOS, TAS, and OSI sensitivity and specificity for prediction of kidney damage (including both values of case-1 and case-2) with respect to control-1 and control-2.

Diagnosis	Cutoff level for kidney damage; (DN or ESRD or both)	Sensitivity (%)	Specificity (%)	AUROC (95% CI)	Asymptotic; Sig.
SPA; (mmol min^−1 L^−1)	≥60.78	76	66	0.798 (0.741–0.855)	0.001
TOS; (µmol H2O2 Eq/L)	≥16.64	89.10	60	0.87 (0.825–0.915)	0.001
TAS; (mmol Trolox Eq/L)	≤0.81	89.10	2	0.198 (0.141–0.255)	0.001
OSI; (arbitrary unit)	≥10.24	80.60	67	0.838 (0.787–0.889)	0.001

AUROC: area under the receiver operating characteristic curve; CI: confidence interval.