Research Article

Improved Rifamycin B Production by Nocardia mediterranei MTCC 14 under Solid-State Fermentation through Process Optimization

Table 2

Yield of rifamycin B from Nocardia mediterranei MTCC 14 using the different levels of production variables of Plackett-Burman design test.

Std. run orderYield  
g/kgds

2−111−1111−1−1−115.21
9111−1−1−11−111−16.38
111−1111−1−1−11−17.84
5−1−11−111−1111−12.89
10−1111−1−1−11−1116.32
111−1111−1−1−11−118.35
6−1−1−11−111−11117.32
12−1−1−1−1−1−1−1−1−1−1−16.97
811−1−1−11−111−118.31
71−1−1−11−111−1117.47
4−11−111−1111−1−19.43
31−111−1111−1−1−18.48

Eleven variables, , glucose, , maltose, , ribose, , galactose, , beef extract, , peanut meal, , ammonium chloride, , ammonium sulphate, , barbital, , pH, and , moisture content, were screened by conducting 12 experiments.