Improved Rifamycin B Production by Nocardia mediterranei MTCC 14 under Solid-State Fermentation through Process Optimization

Table 3

ANOVA of Plackett-Burman design test data for the significant production parameters.

Source	SS	df	MS	value	value
Model	33.52	11	3.35	264.42	0.0478
Glucose	6.29	1	6.29	496.49	0.0286
Maltose	0.34	1	0.34	26.56	0.1220
Ribose	7.86	1	7.86	619.88	0.0256
Galactose	9.21	1	9.21	726.23	0.0236
Beef extract	0.56	1	0.56	44.10	0.0951
Peanut meal	1.98	1	1.98	155.93	0.0509
Ammonium chloride	1.09	1	1.09	85.68	0.0685
Ammonium sulphate	0.057	1	0.057	4.53	0.2796
Barbital	0.013	1	0.013	3.78	0.9522
pH	6.06	1	6.06	478.38	0.0291
Moisture content	0.082	1	0.082	6.44	0.2389
= 0.9996

Galactose, ribose, glucose, and pH were significant ( < 0.05). SS: sum of square, MS: mean of square, df: degree of freedom, value: Fisher’s value, and : probability.