Improved Rifamycin B Production by Nocardia mediterranei MTCC 14 under Solid-State Fermentation through Process Optimization

Table 4

Production variables and their coded and actual values used for optimization of rifamycin B production from mediterranei MTCC 14 by using central composite design.

Production variable	Coded level
	Symbol	−2	−1	0	1	2
Galactose % (w/w)		7.50	8.0	8.50	9.0	9.50
Ribose % (w/w)		2.50	3.0	3.50	4.0	4.50
Glucose % (w/w)		7.50	8.0	8.50	9.0	9.50
pH % (w/w)		6.75	7.0	7.25	7.5	7.75