Influence of Moxifloxacin on Hepatic Redox Status and Plasma Biomarkers of Hepatotoxicity and Nephrotoxicity in Rat

Table 1

Influence of MXF on plasma biomarkers of renal toxicity in rat.

Treatment groups	Urea (mg/dL)	Creatinine (mg/dL)
Control	41.2 ± 3.8	0.37 ± 0.06
MXF-1	51.3 ± 2.1 (25%)	0.54 ± 0.03 (46%)
MXF-2	55.5 ± 3.5 (35%)	0.66 ± 0.05 (78%)
MXF-3	57.2 ± 2.6 (39%)	0.88 ± 0.07 (137%)

Values represent the mean ± SD of six replicates.  Significantly different from control (); values in parenthesis represent % of increase.