Influence of Moxifloxacin on Hepatic Redox Status and Plasma Biomarkers of Hepatotoxicity and Nephrotoxicity in Rat

Table 2

Influence of MXF on plasma biomarkers of hepatotoxicity in rat.

Treatment groups	TBILI (mg/dL)	ALP (U/L)	AST (U/L)	ALT (U/L)
CTRL	0.12 ± 0.02	239.8 ± 5.1	62.4 ± 2.1	21.6 ± 2.4
MXF-1	0.18 ± 0.03 (50%)	262.0 ± 4.2 (9%)	74.2 ± 2.8 (19%)	39.4 ± 2.7 (82%)
MXF-2	0.25 ± 0.02 (108%)	276.0 ± 6.5 (15%)	81.0 ± 3.7 (30%)	49.4 ± 3.1 (129%)
MXF-3	0.28 ± 0.04 (133%)	310.6 ± 8.3 (30%)	87.2 ± 4.6 (40%)	52.8 ± 3.3 (144%)

TBILI: total bilirubin; ALP: alkaline phosphatase; AST: aspartate aminotransferase; ALT: alanine aminotransferase.
Values represent the mean ± SD of six replicates. Significantly different from control (); values in parenthesis represent % of increase.