Research Article
Influence of Moxifloxacin on Hepatic Redox Status and Plasma Biomarkers of Hepatotoxicity and Nephrotoxicity in Rat
Table 3
Influence of MXF on the activities of hepatic antioxidant enzymes in rat.
| | Treatment groups | CAT (μmol H2O2 consumed/min/mg protein) | SOD (units/mg protein) | GST (nmol/min/mg protein) |
| | CTRL | 0.78 ± 0.05 | 13.8 ± 1.3 | 16.3 ± 1.7 | | MXF-1 | 0.64 ± 0.07 (18%) | 10.2 ± 0.8 (26%) | 14.6 ± 1.1 (10%) | | MXF-2 | 0.53 ± 0.03 (32%) | 8.1 ± 1.1 (41%) | 12.5 ± 0.8 (23%) | | MXF-3 | 0.44 ± 0.02 (43%) | 5.5 ± 0.7 (60%) | 10.1 ± 0.7 (38%) |
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Values represent the mean ± SD of six replicates. Significantly different from control (); values in parenthesis represent % of decrease.
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