Synthesis, Spectral Characterization, and Biochemical Evaluation of Antidiabetic Properties of a New Zinc-Diosmin Complex Studied in High Fat Diet Fed-Low Dose Streptozotocin Induced Experimental Type 2 Diabetes in Rats

Table 3

Effect of Zn-diosmin complex on plasma protein and blood urea and serum creatinine levels in rats after 30-day treatment.

Groups	Plasma protein	Blood urea	Serum creatinine
Control	8.88 ± 0.19	25.28 ± 0.90	0.60 ± 0.02
Diabetic control	6.46 ± 0.1	45.10 ± 1.56	1.38 ± 0.02
Diabetic + Zn-diosmin	7.42 ± 0.12	29.33 ± 0.96	0.75 ± 0.01
Diabetic + metformin	8.21 ± 0.17	27.33 ± 0.75	0.68 ± 0.02

Units are expressed as g/dL for plasma protein, mg/dL for blood urea, and serum creatinine.
Values are given as mean ± SEM for groups of six rats in each. One-way ANOVA followed by post hoc test LSD was done. Values are statistically significant at < 0.001. The results were  compared to control rats and compared to diabetic rats.