Bp-13 PLA₂: Purification and Neuromuscular Activity of a New Asp49 Toxin Isolated from Bothrops pauloensis Snake Venom

Figure 8

Twitch-tension response curve of indirectly stimulated BC preparations incubated with 3.56 and 7.12 μM (50 and 100 μg/mL, resp.) at 37°C. (a) Each point represents the mean ± SEM of 3–6 experiments. (b) Percentage of Ach (110 μM) and KCl (20 mM) evoked contracture after Bp-13 administration; compared to control values. ANOVA and followed by Mann-Whitney test for comparison between two groups.

(a)

(b)