Table of Contents Author Guidelines Submit a Manuscript
Biochemistry Research International
Volume 2016, Article ID 1091290, 5 pages
http://dx.doi.org/10.1155/2016/1091290
Research Article

Contribution of Cell Surface Hydrophobicity in the Resistance of Staphylococcus aureus against Antimicrobial Agents

1Animal Biochemistry Division, National Dairy Research Institute, Karnal, Haryana 132001, India
2Animal Biotechnology Division, National Dairy Research Institute, Karnal, Haryana 132001, India
3Dairy Cattle Nutrition Division, National Dairy Research Institute, Karnal, Haryana 132001, India

Received 9 September 2015; Revised 19 November 2015; Accepted 11 January 2016

Academic Editor: Tzi B. Ng

Copyright © 2016 Puja Lather et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Staphylococcus aureus is found in a wide variety of habitats, including human skin, where many strains are commensals that may be clinically significant or contaminants of food. To determine the physiological characteristics of resistant strain of Staphylococcus aureus against pediocin, a class IIa bacteriocin, a resistant strain was compared with wild type in order to investigate the contribution of hydrophobicity to this resistance. Additional clumping of resistant strain relative to wild type in light microscopy was considered as an elementary evidence of resistance attainment. A delay in log phase attainment was observed in resistant strain compared to the wild type strain. A significant increase in cell surface hydrophobicity was detected for resistant strain in both hexadecane and xylene indicating the contribution of cell surface hydrophobicity as adaptive reaction against antimicrobial agents.