Inactivation of Anopheles gambiae Glutathione Transferase ε2 by Epiphyllocoumarin

Figure 6

Pathways for irreversible inhibition [11]. is a measure of the binding affinity for the inactivator for the free enzyme. is a measure of the binding affinity for the inactivator for the enzyme-substrate complex and describes the rate at which inhibitor-enzyme complex is irreversibly transformed into .