Research Article

Changes in Lipid Profiles of HIV+ Adults over Nine Months at a Harare HIV Clinic: A Longitudinal Study

Table 5

Changes in frequency of patients with lipid derangements over 9 months.

ART history
ART naïveART experiencedTotal

Change in frequency of patients with elevated TC over nine months−4.4%, −23.5%, −16.9%, 0.002

Change in frequency of patients with depressed HDL over 9 months−34.8%, = 1.000−5.4%, −9.3%, <0.001

Change in frequency of patients with elevated LDL over 9 months+13.1%, = 1.000−2.6%, −0.6%, 0.092

Change in frequency of patients with elevated TC/HDL ratio over 9 months−17.4%, = 0.688−12.1%, −12.7%, 0.143

Change in frequency of patients with dyslipidemia over 9 months−21.7%, = 0.064−14.2%, < 0.001−15.2%, 0.286

Note: SD: standard deviation; level of significance is set at ; from McNemar chi square tests for paired data by time of visit; from McNemar chi square tests for paired data by ART groups; cutoff values according to NCEP guidelines [20]: elevated TC > 5.2 mmol/L, depressed HDL < 1.1 mmol/L, elevated LDL > 3.2 mmol/L, and elevated TC/HDL ratio > 4.5.