Leaf-Methanolic Extract of Pseudopanax arboreus (Araliaceae) (L. F. Phillipson) Reverses Amitriptyline-Induced Sexual Dysfunction in Male Rats

Table 4

Effects of the leaf-methanolic extract of P. arboreus (ME1 and ME2) on penile licking (PL) and mean intromission interval (MII) (s) of amitriptyline-induced sexually impaired male rats.

	Treatment
Parameter	Day	DW	Viagra	ME1	ME2
PL	1	3.20 ± 0.40^ae	5.21 ± 1.00^ae	3.60 ± 0.50^ae	4.40 ± 0.80^ae
	7	3.60 ± 0.40^ae	6.83 ± 1.00^be	3.80 ± 0.40^ae	4.92 ± 0.80^ae
	14	3.80 ± 0.40^ae	7.17 ± 1.00^ae	4.20 ± 0.40^ae	5.75 ± 0.75^ae
	21	3.72 ± 0.20^ae	6.20 ± 0.90^be	4.42 ± 0.28^ae	5.93 ± 0.90^ae
MII (s)	1	71.60 ± 15.50^ae	32.80 ± 8.00^be	43.60 ± 4.00^ce	54.80 ± 15.00^de
	7	42.20 ± 16.46^af	51.00 ± 10.80^bf	53.40 ± 6.15^bf	20.00 ± 14.32^cf
	14	42.60 ± 15.91^af	38.00 ± 8.36^be	53.80 ± 5.10^cf	24.40 ± 4.97^df
	21	61.00 ± 14.72^ag	38.60 ± 7.45^be	51.80 ± 6.11^cf	38.00 ± 16.36^bg

Values presented as mean ± SEM; DW: distilled water; ME1: methanolic extract dose 1 (46.5 mg/kg); ME2: methanolic extract dose 2 (93 mg/kg); s: seconds; on the same row, values with same letter (a–d) are not significantly different; on the same row, values with different letters are significantly different; on the same column, values with the same letters (e-f) are not significantly different; on the same column, values with different letters are significantly different; PL: penile licking; MII: mean intromission interval (s).