Streptozotocin-Induced Adaptive Modification of Mitochondrial Supercomplexes in Liver of Wistar Rats and the Protective Effect of <i>Moringa oleifera</i> Lam

<div>H<sub>2</sub>O<sub>2</sub> production by mitochondrial respiratory chain measured by Amplex Red (UA) in liver mitochondria from different treatments (C: control; D: diabetic; M: <i>Moringa</i>-treated diabetic groups) oxidizing (a) pyruvate plus malate or (b) succinate as substrates and the effects of respiratory chain inhibitors (R: rotenone; A: antimycin A; Ml: malonate). Mitochondria were studied during state 4 respiration. To correct for the increase in background fluorescence of the Amplex Red/HRP detection system overtime, fluorescence was monitored for a period of ten minutes. This background was subtracted from resorufin trace. Data are means ± SEM (<i>n</i> = 5).</div>

Biochemistry Research International

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Figure 4: Streptozotocin-Induced Adaptive Modification of Mitochondrial Supercomplexes in Liver of Wistar Rats and the Protective Effect of <i>Moringa oleifera</i> Lam 

Figure 4 | Streptozotocin-Induced Adaptive Modification of Mitochondrial Supercomplexes in Liver of Wistar Rats and the Protective Effect of Moringa oleifera Lam 