Research Article

Molecular Modeling of Antimalarial Agents by 3D-QSAR Study and Molecular Docking of Two Hybrids 4-Aminoquinoline-1,3,5-triazine and 4-Aminoquinoline-oxalamide Derivatives with the Receptor Protein in Its Both Wild and Mutant Types

Table 5

Comparison between observed and predicted activities obtained using Y-randomization method.

N311192629313327918202224

Log IC502.3672.4181.2010.7190.961.6051.6031.4961.4051.1931.1670.8971.4731.001
Pred log IC502.1241.8131.2940.8340.8821.4391.4581.6371.6041.7061.0090.8431.6121.442
N302734814154112513232517
Log IC501.7170.9531.2522.3681.9272.131.7011.9581.6111.51.9021.5951.6831.817
Pred log IC501.7061.1251.4892.0841.9822.2591.6861.6141.8281.6461.9321.8001.4701.300