The Binding Affinity of Small Molecules with Yam Tyrosinase (Catechol Oxidase): A Biophysical Study

Table 3

Percent changes in secondary structures of yam tyrosinase in the presence of inhibitors.

% change	Compounds
	Control	Crocin	Hydroquinone	Kojic acid	L-DOPA	C1	C2	C3
α-helix	15.6	9.5	11.9	14.9	8.2	7.2	7.9	7.1
β-sheet	33.8	36.5	35.2	32.3	25.8	39	40.2	30.9
Β-turns	2.1	4.6	4.5	4.5	13.5	5.2	3.2	11

C1: hydroquinone + crocin; C2: kojic acid + hydroquinone; and C3: crocin + L-DOPA. Data presented as the mean of three replicates with standard deviations (n = 3).