Flavonoid-Rich Extract of Dissotis rotundifolia Whole Plant Protects against Ethanol-Induced Gastric Mucosal Damage

Table 2

Effect of the whole plant extract of Dissotis rotundifolia (DRE) and omeprazole on ethanol (EtOH) induced gastric ulcers in SD rats.

Dosage (mg/kg bwt)	Ulcer index		% protection
Negative control		0.88 ± 0.020	—-
Normal control		—	100 ± 0.00
DRE	100	0.26 ± 0.080^ac	70.23 ± 9.05
	300	0.04 ± 0.011^a	95.96 ± 1.25
	500	0.40 ± 0.071^ab	54.55 ± 8.03
Omeprazole	30	0.20 ± 0.090^ac	77.21 ± 10.07

^aSignificant when a group was matched to the negative control group; ^bsignificant when a group was compared to the omeprazole treated group; ^csignificant when a group was compared to 300 mg/kg bwt treated group.