Research Article

Physiochemical, Insecticidal, and Antidiabetic Activities of Senna occidentalis Linn Root

Table 6

Effects of Senna occidentalis (L.) Roots of 80% ethanolic extracts on glucose-loaded rats.

TreatmentsBloods glucose levels mg/dl mean ± S. D.
Time
Groups and dose0 h1 hours2 hours4 hours

Group I “normal vehicle 2% water”68.33b ± 8.5063.67c ± 2.5269.33c ± 11.6857.67c ± 3.21
Group II glucose loading 2 g/kg body wt “positive control”89.00a ± 11.27114.00a ± 13.11138.33a ± 13.32132.67a ± 30.75
Group III glucose loading 2 g/kg + standard glibenclamide 10 mg/kg.93.67a ± 11.6 (5.25%)75.67b,c ± 14.15 (−33.62%)62.00b,c ± 7.81 (−55.18%)57.33b,c ± 3.79 (−56.79%)
Group VI glucose loading 2 g/kg + EtOH of S. o roots 200 mg/kg.101.6a ± 18.4 (14.15%)47.6b,c ± 15.6 (−58.25%)80.33c ± 4.5 (−41.93%)68.2b,c ± 6.9 (−48.59%)

n = 6, a = <0.05 indicates a significant difference compared with diabetic control; b = () indicates a significant difference compared with diabetic control; c = () indicates a significant difference compared with standard drug (glibenclamide), % = level2-level1/level1X100 compared with diabetic control. S. o=Senna occidentalis.