Single-Nucleotide Polymorphisms in XPO5 are Associated with Noise-Induced Hearing Loss in a Chinese Population

Figure 4

SNPrs11077T or G allele in the 3′-UTR of XPO5 differences with the presence or interference of miRNAs (miR-4763-5p, miRNA-5002-3p, and miR-617) was analyzed by dual-luciferase report assay. Negative control means adding an unrelated sequence of miRNAs to the pGL3 vector coupled to the XPO53′-UTR regions (pGL3-3′UTR). Relative luciferase activity was expressed by the ratio of Firefly/Renilla activity. Data were presented as the mean ± SD. and .

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