Modulatory Effect of Probiotics on Proinflammatory Cytokine Levels in Acrylamide-Treated Rats

Table 2

Effect of treatment with the probiotic on the serum levels of IL-6 at different times and across all study groups.

Group	IL-60 (pg/mL)	IL-615 (pg/mL)	IL-630 (pg/mL)	value
1 (acrylamide)	78.83 ± 11.85	111.3 ± 40.77	38.02 ± 6.65	0.51^a
				0.05^b
				0.27^c
2 (acrylamide + LD)	81.03 ± 11.17	26.97 ± 4.23	26.17 ± 3.37	0.05^a
				0.05^b
				0.82^c
3 (acrylamide + HD)	98.68 ± 7.38	51.18 ± 14.85	45.02 ± 4.61	0.05^a
				0.05^b
				0.51^c
4 (control)	114.1 ± 5.91	130.1 ± 20.51	93.95 ± 17.82	0.51^a
				0.05^b
				0.05^c
value	0.08	0.04	0.006	—

Data are presented as mean ± SEM (standard error of mean). LD: low dose of probiotics; HD: high dose of probiotics; bold values show a significant difference (). ^aComparison between days 0 and 15. ^bComparison between the days 0 and 30. ^cComparison between days 15 and 30. Comparison of 4 groups.