Modulatory Effect of Probiotics on Proinflammatory Cytokine Levels in Acrylamide-Treated Rats

Table 3

Effect of treatment with the probiotic on the serum levels of TNF-α at different times and across all study groups.

Group	TNF-α0 (pg/mL)	TNF-α15 (pg/mL)	TNF-α30 (pg/mL)	value
1 (acrylamide)	96.95 ± 7.49	108.0 ± 23.78	94.92 ± 8.73	0.82^a
				0.82^b
				0.82^c
2 (acrylamide + LD)	95.68 ± 3.63	82.34 ± 7.37	96.07 ± 22.95	0.12^a
				0.51^b
				0.82^c
3 (acrylamide + HD)	114.0 ± 5.56	119.7 ± 32.10	73.27 ± 11.04	0.82^a
				0.05^b
				0.27^c
4 (control)	103.3 ± 3.93	100.2 ± 19.63	68.40 ± 4.48	0.82^a
				0.05^b
				0.51^c
value	0.17	0.78	0.25	—

Data are presented as mean ± SEM (standard error of mean). LD: low dose of probiotics; HD: high dose of probiotics; bold values show a significant difference (). ^aComparison between days 0 and 15. ^bComparison between days 0 and 30. ^cComparison between days 15 and 30. Comparison of 4 groups.