Research Article
Baicalein Mediates Mitochondrial Autophagy via miR-30b and the NIX/BNIP3 Signaling Pathway in Parkinson’s Disease
Figure 5
Downregulation of NIX reversed baicalein induced mitochondrial autophagy. The effect of NIX on baicalein induced mitochondrial autophagy was observed through inhibiting the expression of NIX in PD rats by sh-NIX. (a) The expression of NIX was detected by RT-qPCR. (b) Mitochondrial membrane potential was detected by JC-1 fluorescence staining. (c) The expressions of LC3 and P62 were detected by WB. N = 6. The data in the figure are all measurement data and the data are expressed as mean ± standard deviation; one-way ANOVA was used for variance analysis; Tukey's multiple comparisons test was used for post hoc test. .
(a) |
(b) |
(c) |