Diverse Effect of Vitamin C and N-Acetylcysteine on Aluminum-Induced Eryptosis

Figure 6

The effects of AlCl₃ on the formation of reactive oxygen species. (a) Original histogram of DCFDA fluorescence in erythrocytes following exposure for 24 hours to Ringer solution (control, grey areas), AlCl₃ (100 µM, black lines) AlCl₃ (100 µM) in the presence of vit C (0.6 mM, dotted lines) and NAC (1 mM, dashed lines). (b) Geo means ± SD of DCFDA fluorescence in erythrocytes after a 24 hours’ treatment with AlCl₃ (100 µM) in the presence of vit C (AlCl₃ + vit C) and NAC (AlCl₃ + NAC).  < 0.001 compared to the control group, ^# < 0.01 compared to the AlCl₃ group, and ^## < 0.05 compared to the AlCl₃ group.

(a)

(b)