Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations

<div>Cleavage regions considered with the hybrid QM-MM method for the PS2 protein in the <i>γ</i>-secretase enzyme: (upper) the region evaluated for canonical function; (lower) the region evaluated for the moonlighting function.</div>

Biochemistry Research International

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Figure 1

Figure 1: Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations 