Antimalarial, Antioxidant, and Toxicological Evaluation of Extracts of Celtis africana, Grosseria vignei, Physalis micrantha, and Stachytarpheta angustifolia

Table 2

Extract yield and in vitro antiplasmodial activity of selected plants against Plasmodium falciparum 3D7 strain.

Plant extract	Extract yield (%)	Antiplasmodial activity—IC50 (μg/ml)	Classification
Celtis africana	15.2	29.05 ± 1.29	Moderate
Grosseria vignei	7.3	>50	Inactive
Physalis micrantha	5.4	3.51 ± 0.19	High
Stachytarpheta angustifolia	5.7	>50	Inactive
Artemisinin	NA	0.014 ± 0.001	NA

NA—not applicable. Extract yield percentage based on dry pulverized plant material. Classification of antiplasmodial activity based on [26]—high (IC₅₀ < 5 µg/mL), promising (5 < IC₅₀ < 15 µg/mL), moderate (15 < IC₅₀ < 50 µg/mL), and inactive (IC₅₀ > 50 µg/mL).