Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma

Figure 4

miR-210 regulates EFNA3 expression. (a) The prediction for miR-210 binding sites on the EFNA3 transcript. (b) Luciferase activity in HUVECs cotransfected with the indicated miR-210 concentration or EFNA3 luciferase reporter transcript. Data are shown as the ratio of firefly activity to Renilla luciferase activity. (c) Relative EFNA3 expression in the indicated HUVECs was measured by qRT-PCR. (d) Relative EFNA3 protein expression in the indicated HUVECs was measured by WB analysis.

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