Research Article
Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma
Table 2
Univariate and multivariate survival analyses of the prognostic factors associated with survival in pancreatic carcinoma patients (n = 73).
| OS | Univariate analysis | Multivariate analyses | Patients (n) | Median survival time | value | HR | 95% CI | value |
| Gender, male/female | 14/59 | 12/15 | 0.547 | | | | Age, ≤60/>60 | 42/31 | 16/13 | 0.259 | | | | Tumor location, head/body or tail | 58/15 | 14/15 | 0.625 | | | | Tumor size, ≤2/>2 | 23/50 | 17/14 | 0.077 | | | | Duodenal invasion, yes/no | 62/11 | 15/14 | 0.955 | | | | Differentiation, low/median/high | 19/47/7 | 16/14/42 | 0.089 | | | | Lymphatic invasion, yes/no | 46/27 | 16/14 | 0.069 | | | | Vascular invasion, yes/no | 54/19 | 16/9 | 0.075 | | | | Liver metastasis, yes/no | 62/11 | 16/14 | 0.152 | | | | TNM, I, IIA/IIB, and III or IV | 39/34 | 16/13 | 0.022 | | | 0.117 | miR-222, high/low | 36/37 | 16/12 | 0.016 | 1.885 | 1.009–3.232 | 0.022 |
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