Effect of Green Synthesized Iron Oxide Nanoparticles Using Spinach Extract on Triton X-100-Induced Atherosclerosis in Rats

Table 2

Effect of iron oxide nanoparticles on lipid profile parameters in mg/dL.

Group	TC	TG	HDL	LDL	AI
Normal	110.36 ± 1.48^bf	87.35 ± 0.87^bf	69.06 ± 0.95	23.83 ± 1.11^bf	0.59 ± 0.03^bf
Negative	245.26 ± 1.73^ac	220.75 ± 1.34^ac	20.03 ± 0.39^d	181.08 ± 1.31^ac	11.24 ± 0.02^ac
Standard (atorvastatin	114.26 ± 1.78^bjf	90.85 ± 1.48^bjf	71.27 ± 1.43	25.22 ± 1.16^bjf	0.60 ± 0.04^bf
100 µg/kg bw FeO NPs	191.02 ± 1.69^abc	170.51 ± 0.89^abc	50.05 ± 0.06d^ej	106.85 ± 1.50^abc	2.82 ± 0.05^abc
300 µg/kg bw FeO NPs	156.07 ± 0.32^abc	134.02 ± 1.09^abc	59.22 ± 0.35^dej	70.05 ± 0.65^abc	1.64 ± 0.04^abc
500 µg/kg bw Fe ONPs	121.91 ± 1.24^abcf	98.27 ± 1.37^abcf	68.70 ± 0.26^de	33.56 ± 1.19^abcf	0.77 ± 0.05^abc

Values are Mean ± SEM (n = 5). a = significantly () higher than sham. b = significantly () lower than negative control. c = significantly () higher than standard control. d = significantly () lower than normal control. e = significantly () lower than standard control. f = significantly () lower than other treatment groups.