Biochemistry Research International

Research Article

Effect of Green Synthesized Iron Oxide Nanoparticles Using Spinach Extract on Triton X-100-Induced Atherosclerosis in Rats

Table 4

Effect of iron oxide nanoparticles on serum antioxidant markers.


Group	SOD units per millilitre (U/ml)	CAT micromole per hydrogen peroxide per minute (µmol/H₂O₂/min)	GPx units per millilitre (U/ml)

Normal	2.99 ± 0.05^b	57.58 ± 0.84^b	36.03 ± 2.97^b
Negative	1.31 ± 0.05^adc	30.72 ± 0.74^adc	19.43 ± 0.60^ac
Standard (atorvastatin)	2.93 ± 0.05^b	56.02 ± 0.49^b	39.44 ± 0.49^b
100 µg/kg bw Fe ONPs	1.99 ± 0.03^ab	44.35 ± 0.25^ab	20.08 ± 0.33^ac
300 µg/kg bw Fe ONPs	2.23 ± 0.04^ab	49.81 ± 0.39^ab	20.99 ± 0.37^ac
500 µg/kg bw Fe ONPs	2.89 ± 0.04^b	55.69 ± 0.46^b	22.02 ± 0.66^ac

Values are mean ± SEM (n = 5). a = significantly () lower than sham. b = significantly () higher than negative control. c = significantly () lower than standard control. d = significantly () lower than other treatment groups.