Research Article

MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach

Table 1

Differentially expressed miRNAs in OTSCC and BSCC compared with the normal oral mucosa identified by OPLS.

A, DEMs in OTSCC

MicroRNA ID valueFCLog2 FC

hsa-miR-1360.0020.307−1.702
hsa-miR-30e0.0040.383−1.386
hsa-miR-950.0090.403−1.311
hsa-miR-338-3p0.0050.411−1.283
hsa-miR-376a0.0060.420−1.251
hsa-miR-1440.0080.420−1.251
hsa-miR-10.0060.449−1.155
hsa-miR-337-5p0.0040.473−1.081
hsa-miR-133a0.0010.476−1.070
hsa-miR-3770.0050.478−1.066

B, DEMs in BSCC

MicroRNA ID valueFCLof2 FC

hsa-miR-1360.0050.274−1.868
hsa-miR-299-5p0.0060.412−1.280
hsa-miR-1440.0050.430−1.217
hsa-miR-139-5p0.0000.481−1.055
hsa-miR-30a0.0020.482−1.053
hsa-miR-3770.0070.494−1.016
hsa-miR-2040.0050.498−1.006

OTSCC, oral tongue squamous cell carcinoma; BSCC, buccal squamous cell carcinoma; DEM, differentially expressed miRNA; FC, fold change.