Selective Decontamination of the Digestive Tract Reduces Pneumonia and Mortality

Table 3

Odds ratios for pneumonia and mortality in meta-analyses of trials of SDD.

Publication	Year	𝑛/𝑁	Pneumonia	Mortality
			OR [95% confidence interval]
Van den Broucke-Grauls [38]	1991	6/491	0.12 [0.08–0.19]	0.70 [0.45–1.09]
SDD Group [39]	1993	22/4142	0,37 [0.31–0.43]	0.90 [0.79–1.04]
Heyland [40]	1994	24/3312	0.46 [0.39–0.56]	0.87 [0,79–0.97]
Kollef [41]	1994	16/2270	0.15 [0.12–0.17]	0.02 [−0.02–0.05]
Hurley [42]	1995	26/3768	0.35 [0.30–0.42]	0.86 [0.74–0.99]
D’Amico [43]	1998	16/3361	0.35 [0.29–0.41]	0.80 [0.69–0.93]
	1999	21/N.A.	N.A.	0.70 [0.52–0.93]a
Nathens [44]				0.91 [0.71–1.18]b
Liberati [45]	2000	16/3361	0.35 [0,29–0.41]	0.80 [0.69–0.93]
Redman [46]	2001	N.A.	0.36 [0.28–0.46]	N.A.
Liberati [47]	2004	36/6922	0.35 [0.29–0.41]	0.78 [0.68–0.89]
Silvestri [48]	2007	51/8065	N.A.	0.80 [0.69–0.94]
Silvestri [49]	2008	54/9473	0.11 [0.06–0.20]	N.A.
Silvestri [50]	2009	21/4902	N.A.	0.71 [0.61–0.82]
Liberati [51]	2009	36/6914	0.28 [0.20–0.38]	0.75 [0.65–0.87]

asurgical patients; bmedical patients; 𝑛/𝑁: number of trails/patients; OR: odds ratio; N.A.: not available.