Plasminogen Activator Inhibitor-Type I Gene Deficient Mice Show Reduced Influx of Neutrophils in Ventilator-Induced Lung Injury

Figure 2

Thrombin-antithrombin complexes (TATcs) levels in bronchoalveolar lavage fluid and levels of fibrin degradation products in lung homogenate in anesthetized nonventilated control (C) mice, mice ventilated with LV_T or HV_T. Mice were either PAI-1 deficient (PAI-1^−/−, open symbols) or wild type (Wt, closed symbols). Data are represented as individual data with a median. *, indicates statistical significant difference compared to Wt.

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