Table of Contents Author Guidelines Submit a Manuscript
Critical Care Research and Practice
Volume 2011, Article ID 631062, 7 pages
http://dx.doi.org/10.1155/2011/631062
Clinical Study

Assessment of Procalcitonin to Predict Outcome in Hypothermia-Treated Patients after Cardiac Arrest

1Department of Anaesthesia and Intensive Care, Luxembourg Medical Centre (CHL), 1210 Luxembourg, Luxembourg
2Laboratory of Cardiovascular Research, Public Research Centre for Health (CRP-Sante), 1150 Luxembourg, Luxembourg
3Department of Clinical Biology, Luxembourg Medical Centre (CHL), 1210 Luxembourg, Luxembourg

Received 25 May 2011; Revised 14 July 2011; Accepted 10 August 2011

Academic Editor: Romergryko G. Geocadin

Copyright © 2011 Pascal Stammet et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. Adrie, M. Adib-Conquy, I. Laurent et al., “Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like” syndrome,” Circulation, vol. 106, no. 5, pp. 562–568, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Bouadma, C. E. Luyt, F. Tubach et al., “Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial,” The Lancet, vol. 375, no. 9713, pp. 463–474, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Harbarth, K. Holeckova, C. Froidevaux et al., “Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis,” American Journal of Respiratory and Critical Care Medicine, vol. 164, no. 3, pp. 396–402, 2001. View at Google Scholar · View at Scopus
  4. J. U. Jensen, L. Heslet, T. H. Jensen, K. Espersen, P. Steffensen, and M. Tvede, “Procalcitonin increase in early identification of critically ill patients at high risk of mortality,” Critical Care Medicine, vol. 34, no. 10, pp. 2596–2602, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. N. Mongardon, V. Lemiale, S. Perbet et al., “Value of procalcitonin for diagnosis of early onset pneumonia in hypothermia-treated cardiac arrest patients,” Intensive Care Medicine, vol. 36, no. 1, pp. 92–99, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. P. Schuetz, B. Affolter, S. Hunziker et al., “Serum procalcitonin, C-reactive protein and white blood cell levels following hypothermia after cardiac arrest: a retrospective cohort study,” European Journal of Clinical Investigation, vol. 40, no. 4, pp. 376–381, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. M. Fries, D. Kunz, A. M. Gressner, R. Rossaint, and R. Kuhlen, “Procalcitonin serum levels after out-of-hospital cardiac arrest,” Resuscitation, vol. 59, no. 1, pp. 105–109, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Hayashida, T. Kaneko, S. Kasaoka et al., “Comparison of the predictability of neurological outcome by serum procalcitonin and glial fibrillary acidic protein in postcardiac-arrest patients,” Neurocritical Care, vol. 12, no. 2, pp. 252–257, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. M. Holzer, F. Sterz, J. M. Darby et al., “Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest,” New England Journal of Medicine, vol. 346, no. 8, pp. 549–556, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. S. A. Bernard, T. W. Gray, M. D. Buist et al., “Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia,” New England Journal of Medicine, vol. 346, no. 8, pp. 557–563, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. N. Nielsen, J. Hovdenes, F. Nilsson et al., “Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest,” Acta Anaesthesiologica Scandinavica, vol. 53, no. 7, pp. 926–934, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. M. Fries, C. Stoppe, D. Brücken, R. Rossaint, and R. Kuhlen, “Influence of mild therapeutic hypothermia on the inflammatory response after successful resuscitation from cardiac arrest,” Journal of Critical Care, vol. 24, no. 3, pp. 453–457, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. K. Sunde, M. Pytte, D. Jacobsen et al., “Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest,” Resuscitation, vol. 73, no. 1, pp. 29–39, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. C. D. Deakin, J. P. Nolan, J. Soar et al., “European resuscitation council guidelines for resuscitation 2010 section 4. Adult advanced life support,” Resuscitation, vol. 81, no. 10, pp. 1305–1352, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. N. Pichon, J. B. Amiel, B. François, A. Dugard, C. Etchecopar, and P. Vignon, “Efficacy of and tolerance to mild induced hypothermia after out-of-hospital cardiac arrest using an endovascular cooling system,” Critical Care, vol. 11, no. 3, article R71, 2007. View at Publisher · View at Google Scholar · View at PubMed
  16. C. M. Booth, R. H. Boone, G. Tomlinson, and A. S. Detsky, “Is this patient dead, vegetative, or severely neurologically impaired? assessing outcome for comatose survivors of cardiac arrest,” Journal of the American Medical Association, vol. 291, no. 7, pp. 870–879, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  17. I. Jacobs, V. Nadkarni, J. Bahr et al., “Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the international liaison committee on resuscitation,” Resuscitation, vol. 63, no. 3, pp. 233–249, 2004. View at Publisher · View at Google Scholar · View at PubMed
  18. B. Jennett and M. Bond, “Assessment of outcome after severe brain damage,” The Lancet, vol. 1, no. 7905, pp. 480–484, 1975. View at Google Scholar · View at Scopus
  19. “Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia,” American Journal of Respiratory and Critical Care Medicine, vol. 171, pp. 388–416, 2005.
  20. J. V. Roth, “Some unanswered questions about temperature management,” Anesthesia and Analgesia, vol. 109, no. 5, pp. 1695–1699, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  21. M. Christ-Crain, D. Jaccard-Stolz, R. Bingisser et al., “Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial,” The Lancet, vol. 363, no. 9409, pp. 600–607, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  22. V. Nobre, S. Harbarth, J. D. Graf, P. Rohner, and J. Pugin, “Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial,” American Journal of Respiratory and Critical Care Medicine, vol. 177, no. 5, pp. 498–505, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  23. M. Oppert, A. Reinicke, C. Müller, D. Barckow, U. Frei, and K. U. Eckardt, “Elevations in procalcitonin but not C-reactive protein are associated with pneumonia after cardiopulmonary resuscitation,” Resuscitation, vol. 53, no. 2, pp. 167–170, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. P. E. Charles, E. Kus, S. Aho et al., “Serum procalcitonin for the early recognition of nosocomial infection in the critically ill patients: a preliminary report,” BMC Infectious Diseases, vol. 9, article 49, 2009. View at Publisher · View at Google Scholar · View at PubMed
  25. H. K. De Wolf, J. K. Gunnewiek, Y. Berk, J. Van Den Ouweland, and M. De Metz, “Comparison of a new procalcitonin assay from roche with the established method on the brahms kryptor,” Clinical Chemistry, vol. 55, no. 5, pp. 1043–1044, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  26. K. L. Becker, R. Snider, and E. S. Nylen, “Procalcitonin in sepsis and systemic inflammation: a harmful biomarker and a therapeutic target,” British Journal of Pharmacology, vol. 159, no. 2, pp. 253–264, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  27. R. W. Neumar, J. P. Nolan, C. Adrie et al., “Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication a consensus statement from the International Liaison Committee on Resuscitation,” Circulation, vol. 118, no. 23, pp. 2452–2483, 2008. View at Publisher · View at Google Scholar · View at PubMed
  28. M. Tiainen, E. Poutiainen, T. Kovala, O. Takkunen, O. Häppölä, and R. O. Roine, “Cognitive and neurophysiological outcome of cardiac arrest survivors treated with therapeutic hypothermia,” Stroke, vol. 38, no. 8, pp. 2303–2308, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  29. E. F. M. Wijdicks, A. Hijdra, G. B. Young, C. L. Bassetti, and S. Wiebe, “Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review). Report of the quality standards subcommittee of the American academy of neurology,” Neurology, vol. 67, no. 2, pp. 203–210, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  30. J. Arrich, A. Zeiner, F. Sterz et al., “Factors associated with a change in functional outcome between one month and six months after cardiac arrest. A retrospective cohort study,” Resuscitation, vol. 80, no. 8, pp. 876–880, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus