Critical Care Research and Practice / 2012 / Article / Tab 1

Clinical Study

Prediction of Outcome from Community-Acquired Severe Sepsis and Septic Shock in Tertiary-Care University Hospital in a Developing Country

Table 1

Demographic and clinical characteristics of patients with severe sepsis according to outcome.

VariableAll patients
( )
Survivors
( , 48.4%)
Nonsurvivors
( , 51.6%)
value

Male, (%)122 (66.3)56 (63.0)66 (69.5)0.34
Female, (%)62 (33.7)33 (37.0)29 (30.5)
Age, mean (SD)57.1 (17.9)53.7 (18.3)60.3 (17.1)0.01
Hospital stay, days, median (Q1–Q3)13 (6–20)18 (13.5–28)6 (4–12)<0.001
Number of comorbidities, (%)
 048 (26.1)30 (33.7)18 (18.9)0.02
 176 (41.3)33 (37.1)43 (45.3)
 242 (22.8)22 (24.7)20 (21.1)
 ≥318 (9.8)4 (4.5)14 (14.7)
Comorbidities
 Chronic heart failure65 (35.3)22 (24.7)43 (45.3)0.004
 Diabetes mellitus38 (20.7)18 (20.2)20 (21.1)0.89
 Hemiplegic stroke28 (15.2)13 (14.6)15 (15.8)0.82
 Chronic respiratory failure22 (12.0)3 (3.4)19 (20.0)0.001
 Chronic alcoholism19 (10.3)11 (12.4)8 (8.4)0.38
 Metastatic cancer14 (7.6)8 (9.0)6 (6.3)0.49
 Chronic renal failure12 (6.5)4 (4.5)8 (8.4)0.28
 Chronic liver failure12 (6.5)7 (7.9)5 (5.3)0.47
 SAPS II score, median (Q1–Q3)35 (21–53)30 (18–37)43 (25–64)<0.001
Site of infection, (%)
 Lower respiratory tract 121 (65.8)56 (62.9)65 (68.4)0.17
 Meningitis
 Soft tissue
17 (9.2)
15 (8.1)
8 (9.0)
6 (6.7)
9 (9.5)
9 (9.5)
 Urinary tract10 (5.4)9 (10.1)1 (1.0)
 Abdominal (nonsurgical)6 (3.3)2 (2.3)4 (4.2)
 Endocarditis9 (4.9)4 (4.5)5 (5.3)
 Unknown6 (3.3)4 (4.5)2 (2.1)
Number of failed organs, n (%)
 161 (33.2)45 (50.6)16 (16.8)<0.001
 253 (28.8)25 (28.1)28 (29.5)
 ≥370 (38.0)19 (21.3)51 (53.7)
Septic shock, n (%)49 (26.6)14 (15.7)35 (36.8)0.001
Laboratory results
 ESR, mm/h, mean (SD)67.9 (32.6)70.8 (33.5)63.9 (31.5)0.40
 WBC 109/L, mean (SD)15.9 (9.1)15.1 (9.0)16.8 (9.2)0.19
 CRP mg/L, mean (SD)313.5 (183.9)330.1 (186.6)297 (180.8)0.21

SD: standard deviation; Q1–Q3: 1st quartile–3rd quartile; SAPS II: simplified acute physiology score II; ESR: erythrocyte sedimentation rate; WBC: white blood cells; CRP: C-reactive protein.

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