Clinical Study
Prediction of Outcome from Community-Acquired Severe Sepsis and Septic Shock in Tertiary-Care University Hospital in a Developing Country
Table 1
Demographic and clinical characteristics of patients with severe sepsis according to outcome.
| | Variable | All patients
() | Survivors
(, 48.4%) | Nonsurvivors
(, 51.6%) | value |
| | Male, (%) | 122 (66.3) | 56 (63.0) | 66 (69.5) | 0.34 | | Female, (%) | 62 (33.7) | 33 (37.0) | 29 (30.5) | | | Age, mean (SD) | 57.1 (17.9) | 53.7 (18.3) | 60.3 (17.1) | 0.01 | | Hospital stay, days, median (Q1–Q3) | 13 (6–20) | 18 (13.5–28) | 6 (4–12) | <0.001 | | Number of comorbidities, (%) | | | | | | 0 | 48 (26.1) | 30 (33.7) | 18 (18.9) | 0.02 | | 1 | 76 (41.3) | 33 (37.1) | 43 (45.3) | | | 2 | 42 (22.8) | 22 (24.7) | 20 (21.1) | | | ≥3 | 18 (9.8) | 4 (4.5) | 14 (14.7) | | | Comorbidities | | | | | | Chronic heart failure | 65 (35.3) | 22 (24.7) | 43 (45.3) | 0.004 | | Diabetes mellitus | 38 (20.7) | 18 (20.2) | 20 (21.1) | 0.89 | | Hemiplegic stroke | 28 (15.2) | 13 (14.6) | 15 (15.8) | 0.82 | | Chronic respiratory failure | 22 (12.0) | 3 (3.4) | 19 (20.0) | 0.001 | | Chronic alcoholism | 19 (10.3) | 11 (12.4) | 8 (8.4) | 0.38 | | Metastatic cancer | 14 (7.6) | 8 (9.0) | 6 (6.3) | 0.49 | | Chronic renal failure | 12 (6.5) | 4 (4.5) | 8 (8.4) | 0.28 | | Chronic liver failure | 12 (6.5) | 7 (7.9) | 5 (5.3) | 0.47 | | SAPS II score, median (Q1–Q3) | 35 (21–53) | 30 (18–37) | 43 (25–64) | <0.001 | | Site of infection, (%) | | | | | | Lower respiratory tract | 121 (65.8) | 56 (62.9) | 65 (68.4) | 0.17 | Meningitis
Soft tissue | 17 (9.2)
15 (8.1) | 8 (9.0)
6 (6.7) | 9 (9.5)
9 (9.5) | | | Urinary tract | 10 (5.4) | 9 (10.1) | 1 (1.0) | | | Abdominal (nonsurgical) | 6 (3.3) | 2 (2.3) | 4 (4.2) | | | Endocarditis | 9 (4.9) | 4 (4.5) | 5 (5.3) | | | Unknown | 6 (3.3) | 4 (4.5) | 2 (2.1) | | | Number of failed organs, n (%) | | | | | | 1 | 61 (33.2) | 45 (50.6) | 16 (16.8) | <0.001 | | 2 | 53 (28.8) | 25 (28.1) | 28 (29.5) | | | ≥3 | 70 (38.0) | 19 (21.3) | 51 (53.7) | | | Septic shock, n (%) | 49 (26.6) | 14 (15.7) | 35 (36.8) | 0.001 | | Laboratory results | | | | | | ESR, mm/h, mean (SD) | 67.9 (32.6) | 70.8 (33.5) | 63.9 (31.5) | 0.40 | | WBC 109/L, mean (SD) | 15.9 (9.1) | 15.1 (9.0) | 16.8 (9.2) | 0.19 | | CRP mg/L, mean (SD) | 313.5 (183.9) | 330.1 (186.6) | 297 (180.8) | 0.21 |
|
|
SD: standard deviation; Q1–Q3: 1st quartile–3rd quartile; SAPS II: simplified acute physiology score II; ESR: erythrocyte sedimentation rate; WBC: white blood cells; CRP: C-reactive protein.
|
