Review Article
Manipulation of the Complement System for Benefit in Sepsis
Table 2
Protective effects of anti-C5a rabbit IgG in CLP rats.
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*Expressed as percent of all rats in each group (). The M region of rat C5a involved amino acid residues 17–36 while the C region involved residues 58–77. Peptides were covalently linked to keyhole limpet hemocyanin followed by immunizations of rabbits. Antibodies were isolated by antigen affinity purification. Adapted from data in [13]. **Time (hr) of antibody infusion after CLP. |