Derecruitment Test and Surfactant Therapy in Patients with Acute Lung Injury

Table 2

Changes in hemodynamics, arterial blood gases, and lung mechanics in patients with acute lung injury.

Parameter	Group	After the tests	After the FOB	1 hr	2 hrs	4 hrs	8 hrs	16 hrs	24 hrs	32 hrs	48 hrs
CI, L/min/m^2	ST	5.03±1.04	4.77±1.16	5.05±1.10	4.79±1.20	4.98±1.15	4.99±1.35	4.89±1.16	4.62±1.03	4.76±0.93	4.35±0.74
	CT	3.85±1.84	3.90±1.86	3.66±2.09	3.80±1.88	4.20±2.37	3.96±1.82	3.63±1.81	2.75±0.83	3.23±1.10	3.42±1.23
GEDVI, mL/m^2	ST	863±180	690±88	743±206	799±243	797±218	787±142	752±173	743±207	800±275	714±89
	CT	694±131	675±149	714±172	755±156	749±145	727±111	676±140	694±84	660±108	710±97
EVLWI, mL/kg PBW	ST	19±6	23±5	17±6	18±8	17±5	18±4	19±4	18±5^a	18±3^a	18±5
	CT	14±4	15±5	14±6	16±7	14±6	13±6	15±8	11±2	10±3	11±5
PaO2/FiO2, mm Hg	ST	157±62	142±41	131±49	159±58	168±71	147±45	162±126	146±32	219±98	189±41
	CT	119±40	154±79	139±50	142±46	162±76	168±75	188±89	196±99	205±84	195±107
PaCO2, mm Hg	ST	56±9^a	58±9	53±8	51±7	49±11	50±11	54±8^a	50±15	44±11	47±17
	CT	45±6	44±11	42±10	44±11	41±11	41±11	40±6	40±3	41±3	43±4
EtCO2, mm Hg	ST	44±7	45±7	43±7	42±6	40±5	40±6	39±5	40±11	38±9	41±12
	CT	33±10	37±11	34±11	33±9	32±8	34±8	33±7	31±6	33±6	37±6
FiO2	ST	0.58±0.20	0.63±0.25	0.70±0.22	0.63±0.15	0.62±0.13	0.58±0.13	0.64±0.16	0.59±0.08	0.56±0.08	0.50±0.06
	CT	0.67±0.14	0.70±0.18	0.63±0.11	0.63±0.11	0.62±0.11	0.59±0.11	0.58±0.10	0.54±0.05	0.56±0.08	0.55±0.04
PEEP, cm H2O	ST	9±6	11±6	12±7	10±6	10±6	10±7	10±5	11±6	11±6	9±4
	CT	9±4	8±4	9±5	10±5	10±5	9±4	9±4	9±3	9±4	9±4
Compliance, mL/cm H2O	ST	33±6	33±6	34±5	36±8	37±8	34±8	34±2	31±3	35±3	38±7
	CT	28±7	32±8	31±6	28±5	28±5	30±7	31±9	30±7	32±9	30±7

Data are presented as mean ± standard deviation. ^aintergroup difference (𝑃<0.05).
After the tests: after both recruitment maneuver and de-recruitment test; ST: surfactant therapy; CT: conventional therapy; FOB: fiberoptic bronchoscopy; CI: cardiac index; GEDVI: global end-diastolic volume index; EVLWI: extravascular lung water index; PBW: predicted body weight; PEEP: positive end-expiratory pressure.