Table 1: Anthropometric, respiratory, and cardiovascular data under facial and different nasal interfaces.

VariablesV40N40N60

Baseline ( , FiO2 = 0.21)

Gender (M/F)9/68/77/8
Age (years)68.0 (62.0–78.0)70.0 (61.0–76.0)64.0 (63.0–70.0)
BMI (kg/m2)26.5 (22.5–29.1)25.0 (21.4–28.0)25.7 (21.2–28.9)
pH7.45 (7.44–7.48)7.47 (7.43–7.49)7.46 (7.42–7.47)
PaCO2 (mmHg)37.5 (35.0–42.1)39.1 (37.3–41.5)39.6 (33.4–42.5)
PaO2/FiO2322.4 (295.6–374.3)342.8 (295.7–371.9)350.9 (304.3–363.8)
a/A PO20.674 (0.587–0.764)0.723 (0.652–0.745)0.718 (0.659–0.765)
PaO2 (mmHg)67.7 (62.1–78.6)72.0 (62.1–78.1)73.7 (63.9–76.4)
SpO2 (%)94 (93–96)95 (91–96)95 (93–97)
HR (bpm)75.0 (62.0–97.0)78.0 (72.0–85.0)74.0 (68.0–84.0)
MAP (mmHg)94.0 (90.0–107.0)102.0 (92.0–112.0)109.0 (100.0–117.0)

End of bronchoscopy ( , FiO2 = 0.50)

pH7.41 (7.38–7.44)*7.41 (7.38–7.44)*7.40 (7.36–7.40)*
PaCO2 (mmHg)42.7 (41.0–44.4)*43.2 (37.9–47.6)*43.6 (42.4–48.0)*,+
PaO2/FiO2165.0 (127.4 −199.2)*140.6 (125.6–153.6)*244.8 (181.6–366.8)+,++
a/A PO20.265 (0.207–0.326)*0.224 (0.204 - 0.249)*0.401 (0.295–0.604)*,+,++
PaO2 (mmHg)82.5 (63.7–99.6)70.3 (62.8–76.8)122.4 (90.8–183.4)*,++
SpO2 (%)94 (92–96)92 (90–95)98 (97–99)*,+,++
HR (bpm)90 (76–110)*84 (80–101)84 (70–100)*
MAP (mmHg)108.0 (92.0–126.0)99.0 (94.0–105.0)103.0 (93.0–117.0)
Duration (min)14.0 (10.0–16.0)15.0 (12.0–16.0)15.0 (9.0–20.0)

10 minutes after bronchoscopy ( , FiO2 = 0.35)

pH7.42 (7.40–7.45)*7.41 (7.39–7.44)*,**7.40 (7.40–7.44)*,**
PaCO2 (mmHg)42.2 (39.7–43.2)*43.4 (41.0–45.7)*40.7 (38.0–45.5)
PaO2/FiO2248.6 (206.6–274.3)*,**224.3 (206.6–249.1)*,**278.8 (222.9–304.0)*
a/A PO20.441 (0.342–0.515)*,**0.421 (0.352- 0.446)*,**0.480 (0.389- 0.536)*
PaO2 (mmHg)87.0 (72.3–101.8)78.5 (72.3–87.2)97.6 (78.0–106.4)*,**
SpO2 (%)95 (92–98)93 (91–95)95 (95–98)**,+
HR (bpm)82.0 (75.0–90.0)**80.0 (79.0–91.0)*76.0 (64.0–89.0)**
MAP (mmHg)91.0 (83.0–103.0)94.0 (85.0–98.0)**96.0 (87.0–108.0)

Values are median (1st–3rd quartiles). V40, N40: patients that received oxygen (40 L/min, FiO2 = 0.5) through a Venturi mask and nasal prong; respectively, N60: patients that received oxygen (60 L/min, FiO2 = 0.5) through a nasal high-flow interface; baseline: FiO2 = 0.21; end of bronchoscopy: airflow according to V40, N40, and N60, FiO2 = 0.5; 10 min after bronchoscopy: 15 L/min, FiO2 = 0.35; PaCO2 and PaO2: arterial partial pressures of CO2 and O2; respectively, BMI: body mass index; PaO2/FiO2: ratio between PaO2 and inspiratory fraction of O2; a/A PO2: ratio between arterial and alveolar PO2; SpO2: peripheral oxygen saturation; HR: heart rate; MAP: mean arterial pressure, duration: length of bronchoscopy. *Significantly different from ; **significantly different from ; +significantly different from V40; ++significantly different from N40; significance level = 5%.