Critical Care Research and Practice

Clinical Study

Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock

Table 4

Hemodynamic, perfusion and microcirculatory parameters in 45 patients evaluated with sublingual SDF videomicroscopy.


	Lactate < 2.5 mmol/L	Lactate ≥ 2.5 mmol/L

n (%)	14 (31%)	31 (69%)
NE (ug/kg/min)	0.2 [0.09–0.39]	0.48 [0.22–0.93]*
Lactate (mmol/l)	1.4 [1.2–2.1]	5.8 [3.9–8.4]*
ScvO₂ (%)	73 [67–77]	71 [66–78]
TVD (n/mm)	12.9 [10.7–13.9]	12.9 [11.1–14.9]
PVD (n/mm)	10.5 [9.5–12]	10.1 [6.6–12.4]
PPV (%)	87.3 [81.6–90.6]	75.5 [60.9–86.4]*
MFI	2.44 [2.25–2.61]	2.11 [1.7–2.32]*
Het MFI	0.33 [0.18–0.49]	0.42 [0.27–0.72]

*
Data are shown as median [interquartile range] or percentage. NS: nonsignificant (). NE: norepinephrine; ScvO₂: central venous oxygen saturation; P(cv-a)CO₂: central venous-to-arterial PCO₂ difference; TVD: total vascular density; PVD: perfused vascular density; PPV: percentage of perfused vessels; MFI: microvascular flow index; Het MFI: MFI heterogeneity.