The End-Organ Impairment in Liver Cirrhosis: Appointments for Critical Care

Table 6

Diagnostic criteria of hepatorenal syndrome.

Chronic or acute hepatic disease with advanced hepatic failure and portal hypertension.
A plasma creatinine concentration above 1.5 mg/dL (133 micromol/L) that progresses over days to weeks.
The absence of any other apparent cause for the renal disease, including shock, ongoing bacterial infection, current or recent treatment with nephrotoxic drugs, and the absence of ultrasonographic evidence of obstruction or parenchymal renal disease.
Urine red cell excretion of less than 50 cells per high power field (when no urinary catheter is in place) and protein excretion less than 500 mg/day.
Lack of improvement in renal function after volume expansion with intravenous albumin (1 g/kg of body weight per day up to 100 g/day) for at least two days and withdrawal of diuretics.