| | Risk Factor | Number of studies | Odds ratio or mean difference* (95% CI) | value for
interaction | Inconsistency
2 |
| | Age | | | | | | Surgical | 17 | 5.35 [2.84, 7.86] | 0.99 | 96% | | Mixed | 6 | 4.95 [2.27–7.63] | 0.81 | 97% | | Medical | 3 | 7.61 [4.77, 10.44] | 0.17 | 0% | | Diabetes | | | | | | Surgical | 11 | 1.61 [1.41, 1.83] | 0.61 | 31% | | Mixed | 4 | 1.09 [1.07, 1.11] | <0.001 | 0% | | Hypertension | | | | | | Surgical | 7 | 1.34 [1.04, 1.73] | 0.53 | 68% | | Mixed | 2 | 0.68 [0.45, 1.05] | 0.08 | 49% | | Baseline creatinine* | | | | | | Surgical | 8 | 0.20 [−0.02, 0.42] | 0.89 | 99% | | Heart Failure | | | | | | Surgical | 9 | 2.19 [1.92, 2.5] | 0.34 | 8% | | Mixed | 4 | 1.51 [1.47, 1.55] | 0.003 | 0% | | Sepsis/SIRS | | | | | | Surgical | 2 | 2.69 [1.28, 5.64] | 0.57 | 47% | | Mixed | 4 | 2.52 [1.36, 4.69] | 0.45 | 87% | | Medical | 2 | 8.58 [1.56, 47.22] | 0.34 | 95% | | Nephrotoxic drugs | | | | | | Surgical | 4 | 1.25 [0.92, 1.71] | 0.34 | 0% | | Mixed | 2 | 2.12 [1.04, 4.32] | 0.41 | 64% | | Severity of disease* | | | | | | Surgical | 5 | 5.69 [3.25, 8.14] | 0.40 | 88% | | Mixed | 3 | 10.66 [3.37, 17.95] | 0.35 | 96% | | Medical | 2 | 5.32 [3.98, 6.65] | 0.18 | 0% | | Hypotension/shock | | | | | | Surgical | 4 | 2.48 [1.3, 4.72] | 0.74 | 57% | | Mixed | 4 | 3.44 [1.09, 10.89] | 0.79 | 92% | | Pressors/inotropes | | | | | | Surgical | 5 | 5.36 [2.39, 12.03] | 0.81 | 91% | | Mixed | 2 | 3.41 [1.87, 6.20] | 0.45 | 19% | | High risk surgery/emergency surgery | | | | | | Surgical | 6 | 3.79 [2.91, 4.94] | 0.04 | 33% | | Mixed | 4 | 1.14 [0.64, 2.02] | 0.04 | 91% |
|
|
