Critical Care Research and Practice / 2012 / Article / Tab 4

Research Article

Risk Factors for Development of Acute Kidney Injury in Critically Ill Patients: A Systematic Review and Meta-Analysis of Observational Studies

Table 4

Subgroups analysis.

Risk FactorNumber of studiesOdds ratio or mean difference* (95% CI) value for
interaction
Inconsistency
2

Age
 Surgical175.35 [2.84, 7.86]0.9996%
 Mixed64.95 [2.27–7.63]0.8197%
 Medical37.61 [4.77, 10.44]0.170%
Diabetes
 Surgical111.61 [1.41, 1.83]0.6131%
 Mixed41.09 [1.07, 1.11]<0.0010%
Hypertension
 Surgical71.34 [1.04, 1.73]0.5368%
 Mixed20.68 [0.45, 1.05]0.0849%
Baseline creatinine*
 Surgical80.20 [−0.02, 0.42]0.8999%
Heart Failure
 Surgical92.19 [1.92, 2.5]0.348%
 Mixed41.51 [1.47, 1.55]0.0030%
Sepsis/SIRS
 Surgical22.69 [1.28, 5.64]0.5747%
 Mixed42.52 [1.36, 4.69]0.4587%
 Medical28.58 [1.56, 47.22]0.3495%
Nephrotoxic drugs
 Surgical41.25 [0.92, 1.71]0.340%
 Mixed22.12 [1.04, 4.32]0.4164%
Severity of disease*
 Surgical55.69 [3.25, 8.14]0.4088%
 Mixed310.66 [3.37, 17.95]0.3596%
 Medical25.32 [3.98, 6.65]0.180%
Hypotension/shock
 Surgical42.48 [1.3, 4.72]0.7457%
 Mixed43.44 [1.09, 10.89]0.7992%
Pressors/inotropes
 Surgical55.36 [2.39, 12.03]0.8191%
 Mixed23.41 [1.87, 6.20]0.4519%
High risk surgery/emergency surgery
 Surgical63.79 [2.91, 4.94]0.0433%
 Mixed41.14 [0.64, 2.02]0.0491%

CI: confidence interval, SIRS: systemic inflammatory response syndrome.

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