Critical Care Research and Practice / 2012 / Article / Tab 1

Clinical Study

Systemic and Urinary Neutrophil Gelatinase-Associated Lipocalins Are Poor Predictors of Acute Kidney Injury in Unselected Critically Ill Patients

Table 1

Group characteristics.

Patients who never developed AKIPatients who developed AKIPatients with AKI on admission value
( )( )( )

Age (years) 58.8 (16.1)67.1 (15.8)74.4 (9.4)<0.05
Gender (male) (%)37 (64.9%)21 (67.7%)32 (61.5)0.84
Weight (kg)75.7 (14.7)81.6 (14.9)81.1 (19.7)0.17
Height (cm)176.0 (8.4)175.2 (8.5)171.2 (17.1)0.12
APACHE II score18.5 (9.4)19.3 (8.3)23 (11.5)0.06
SAPS II35.9 (12)42.8 (15)47.1 (14.8)<0.05
RIFLE baseline sCr ( mol/L) 69.9 (18.7)77.9 (15.9)76.3 (19.8)0.16
sUrea (mmol/L)7.9 (5.9–11.2)11.7 (8.1–17.2)12.4 (8.1–22.4)<0.05
sCr ( mol/L)62 (50–78)86 (72–104)110 (73–177)<0.05
sNGAL (ng/mL)269 (180–398)307 (187–460)343 (238–652)<0.05
uNGAL (ng/mL)99 (41–301)149 (52–405)289 (92–602)<0.05
uNGALcorr (mg/molCr)23 (9–64)40 (13–142)23 (8–101)0.05
Primary diagnosis ( ) (%)
 CPB1 (1.7%)2 (6.4%)0.25
 Cardiovascular failure1 (1.7%)4 (12.9%)4 (7.7%)0.11
 Cerebrovascular event2 (3.5%)0 (0%)0 (0%)
 Hemorrhagic shock7 (12.3%)1 (3.2%)5 (9.6%)0.37
 Multiple trauma3 (5.3%)2 (6.4%)1 (1.9%)0.55
 Elective major surgery1 (1.8%)1 (3.2%)5 (9.6%)0.15
 Respiratory failure22 (38.6%)10 (32.2%)14 (26.9%)0.43
 Septic shock20 (35.1%)11 (35.5%)24 (46.2%)0.44
Admission category ( ) (%)
 Medical27 (47.4%)14 (45.2%)21 (40.4%)0.76
 Surgical30 (52.6%)17 (54.8%)31 (59.6%)0.76
Days from admission until AKI (median and range)NA2 (1-2)0
Worst AKI score in ICU ( ) (%)
 Risk 25 (80%)22 (42%)<0.05
 Injury4 (12%)13 (25%)0.19
 Failure2 (6%)17 (32%)0.006
CVVH1 (2%)3 (10%)8 (15%)<0.05
LOS (days)5 (3–8)8 (5–18)6 (3–9)0.001
ICU mortality0 4 (13%)8 (15%)<0.05
Hospital mortality4 (7.0%)5 (16.1%)15 (29%)<0.05

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