Research Article

A High Ductal Flow Velocity Is Associated with Successful Pharmacological Closure of Patent Ductus Arteriosus in Infants 22–27 Weeks Gestational Age

Table 2

Characteristics at time of echocardiography.

Ductus closed ( )Ductus persistent ( )

Age at echocardiography, days (range)2 (0–7)2 (0–33)0.079
Ventilator (%)10 (34)16 (59)0.108
Ventilator MAP, cmH2O (range)8 (6–14)9 (7–12)0.220
CPAP (%)19 (66)11 (41)0.108
CPAP pressure, cmH2O (range)5 (4–7)5 (3–7)0.618
Fraction of inspired oxygen, % (range)25 (21–52)27 (21–42)0.848
Systolic blood pressure1, mmHg (range)47 (37–62)47 (35–84)0.987
Ductal diameter, mm (range)1.7 (0.9–3.0)1.8 (1.0–3.0)0.399
Maximal ductal flow velocity, m/s (range)1.6 (0.5–2.7)1.1 (0.7–2.9)0.023
LA/Ao (range)1.5 (1.2–2.8)1.7 (1.1–3.5)0.198

121 versus 15 infants had an arterial catheter which enabled blood pressure measurements.