Research Article

Sepsis and AKI in ICU Patients: The Role of Plasma Biomarkers

Table 2

Comparison of biochemical markers between septic patients and nonseptic patients.

Septic pts ( )Nonseptic pts ( )P value

Male sex (%)33.966.70.0013
Age (years)69 (48.7 to 74.2)67 (59 to 75)0.83
Creatinine (mg/dL)1.64 (1.04 to 2.97)1.0 (0.8 to 1.0)<0.001
NGAL (ng/mL)459 (213 to 744)120 (79 to 174)<0.001
AOPP (μmol/L)505.1 (307.6 to 643.5)115.7 (79.2 to 181.7)<0.001
BNP (pg/mL)409 (212 to 673)135 (61 to 275)<0.001
Sofa score10 (8 to 12)5 (4 to 5)<0.001
Died (%)32.116.70.08

NGAL: neutrophil gelatinase-associated lipocalin; AOPP: advanced oxidation protein products; BNP: brain natriuretic peptide; SOFA score: sequential organ failure assessment.