Research Article

Sepsis and AKI in ICU Patients: The Role of Plasma Biomarkers

Table 4

Comparison of biochemical markers between AKI septic patients and AKI nonseptic patients.

AKI septic pts ( )AKI nonseptic pts ( )P value

Male sex (%)29.278.60.0033
Age (years)69 (50 to 71)76 (69 to 80)0.0067
Creatinine (mg/dL)2.3 (1.5 to 3.4)1.0 (0.8 to 1.6)<0.001
NGAL (ng/mL)572 (308 to 819)312 (141 to 633)0.15
AOPP (μmol/L)554.0 (366.8 to 717.6)118.9 (90.1 to 152.5)<0.001
BNP (pg/mL)576 (291 to 1723)305 (134 to 559)0.1055
Sofa score11 (8 to 13)5 (5 to 5)<0.001
Died (%)45.842.90.85

NGAL: neutrophil gelatinase-associated lipocalin; AOPP: advanced oxidation protein products; BNP: brain natriuretic peptide; SOFA score: sequential organ failure assessment.