Is Vitamin D Insufficiency Associated with Mortality of Critically Ill Patients?
Table 3
Comparison of patients while separated four groups according to quartiles of admission vitamin D levels.
Variable
Group 1 (1st quartile) ()
Group 2 (2nd quartile) ()
Group 3 (3rd quartile) ()
Group 4 (4th quartile) ()
value
25(OH)D level (ng/mL)
4.45 [3.13–6.19]
10.85 [9.04–13.22]
17.79 [16.44–19.92]
38.74 [31.65–47.47]
0.0001
Age (years)
65.5 [57.75–76]
71 [60–80]
65 [56.75–74]
62.5 [35.7–77]
0.115
Male gender
25 (50%)
25 (49%)
31 (62%)
32 (64%)
0.096
Length of hospital stay prior to ICU admission (days)
5 [2–14]
3 [2–6]
4 [2–15]
4 [1.75–11.5]
0.274
Length of ICU stay (days)
8,5 [5.75–20]
8 [5–11]
11 [6–15.25]
6 [4–12.5]
0,124
On admission
APACHE II score
25.5 [20–30.25]
25 [18–28]
22 [16–26.25]
19 [16–25.25]
0.017
SOFA score
10 [6.75–14]
7 [4–9]
8 [6–10]
6 [4–9]
0.001
Procalsitonin levels (ng/mL)
4.62 [1.12–24]
1.67 [0.3–8.3]
1.73 [0.54–6.3]
1.1 [0.28–4.5]
0.047
Calcium, ionized (mmol/L)
1.09 [1.0–1.2]
1.12 [1–1.23]
1.19 [1.05–1.25]
1.22 [1.12–1.33]
0.001
Albumin (g/dL)
2.3 [1.97–2.8]
2.7 [2.4–3.2]
2.8 [2.2–3.125]
2.8 [2.38–3.33]
0.002
Creatinine (mg/dL)
2.42 [1.32–3.8]
1.62 [0.84–3.23]
1.42 [0.8–3.28]
1.34 [0.7–2.75]
0.019
On admission
Sepsis/septic shock
28 (56%)
15 (29.4%)
20 (40%)
9 (18%)
0.001
Renal dysfunction
26 (52%)
13 (21%)
16 (32%)
7 (14%)
0.0001
During ICU stay
Invasive mechanical ventilation
29 (58%)
18 (35.3%)
16 (32%)
13 (26%)
0.001
Renal replacement therapy
25 (50%)
17 (33.3%)
17 (35.4%)
10 (20%)
0.003
ICU mortality
23 (46%)
19 (37.3%)
20 (40%)
14 (38%)
0.096
Values are presented as median [interquartile range] or (%); APACHE: acute physiology and chronic health evaluation, SOFA: sequential organ failure assessment, and ICU: Intensive care unit.
