Research Article

Acute Kidney Injury after Major Abdominal Surgery: A Retrospective Cohort Analysis

Table 5

Univariate and multivariate analysis to determine predictors of in-hospital mortality.

VariableUnadjusted OR
(95% CI)
Adjusted OR
(95% CI)

Preoperative characteristics
 Age (per year)1.1 (1.06–1.2)<0.00011.07 (1.02–1.1)0.014
 Male1.1 (0.5–2.2)0.887
 Caucasian 1.3 (1.2–9.7)0.831
 Solid malignancy1.5 (0.7–3.2)0.287
 ASA physical status IV/V15.4 (6.7–35.6)<0.00019.1 (2.9–27.5)<0.0001
 Nonrenal RCRI (per point)2.6 (1.5–4.3)<0.00011.6 (0.8–3.2)0.213
 Preoperative hemoglobin (per g/dL)0.63 (0.5–0.8)<0.00010.9 (0.6–1.2)0.501
 Preoperative SCr (per mg/dL)2.3 (1.3–3.9)0.0030.6 (0.3–1.4)0.268
 Urgency surgery4.2 (1.9–8.9)<0.00011.9 (0.6–6.3)0.320
Type of surgery
 Colorectal1.3 (0.6–2.7)0.516
 Gastric0.7 (0.2–1.9)0.471
 Hepatobiliary and pancreatic10.2 (0.03–1.5)0.116
 Small bowel0.8 (0.1–6.2)0.800
 Esophageal3.4 (0.7–16.5)0.130
 Other surgery1.8 (0.7–5)0.242
 Nonrenal SAPS II (per point)1.13 (1.09–1.2)<0.00011.08 (1.04–1.1)<0.0001
 Fluid balance (per liter)20.9 (0.8–1.1)0.918
 Postoperative AKI11.2 (4.8–26.2)<0.00013.7 (1.2–11.7)0.024

OR: odds ratio. CI: confidence interval. ASA: American Society of Anesthesiologists. RCRI: Revised Cardiac Risk Index. SCr: serum creatinine. SAPS II: Simplified Acute Physiology Score, version II. AKI: acute kidney injury. 1Hepatobiliary and pancreatic surgery includes gallbladder surgery ( ), hepatic surgery ( ), pancreatic surgery ( ), and bile ducts surgery ( ). 2Fluid balance within the first two postoperative days.